Clinical Trial

The Effects of Acute Erythropoietin on Hepcidin and Dietary Iron Absorption Following Military-relevant Exercise in Energy Deficit: Pilot Study

Study acronym: IRON BOOST
Active, Not Recruiting
View on ClinicalTrials.gov →
Summary
Military personnel frequently experience declines in iron status during training and when in the field, which may compromise performance. The overall purpose of this study is to determine why the decline in iron status occurs and potential countermeasures. Participants will be given an acute dose of erythropoietin (EPO) or placebo and will complete a 90-minute load carriage exercise test. Prior to the main trial, this pilot study will determine the optimal approach to assess iron absorption following exercise (red blood cell incorporation or plasma isotope appearance), the percentage of iron incorporated into red blood cells with EPO compared to placebo, and the timing of the intervention.
Trial Details
NCT Number NCT07517562
Lead Sponsor Pennington Biomedical Research Center
Conditions Iron Absorption
Enrollment 6 participants
Start Date 2025-09-01
Primary Completion 2025-12-31 (estimated)
Study Completion 2026-05-01 (estimated)
Updated on ClinicalTrials.gov 2026-04-08