Clinical Trial

Adductor Canal Block Combined With Local Infiltration Analgesia vs Local Infiltration Analgesia Alone for Postoperative Pain in Total Knee Arthroplasty

Study acronym: ADB_01
Completed
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Summary
Total knee arthroplasty (TKA) is commonly associated with significant postoperative pain, which may impair early mobilization and functional recovery. Multimodal analgesia techniques are widely used to improve postoperative pain control while minimizing opioid consumption. Local infiltration analgesia (LIA) is a commonly used method; however, its effectiveness may be limited when used alone. The adductor canal block (ACB) provides effective analgesia while preserving quadriceps muscle strength. This prospective randomized controlled study aims to compare the effectiveness of adductor canal block combined with local infiltration analgesia versus local infiltration analgesia alone on postoperative pain scores in patients undergoing total knee arthroplasty. The primary outcome is postoperative pain assessed using the NRS at multiple time points within the first 48 hours. Secondary outcomes include opioid consumption, functional recovery parameters and hemodynamic parameters. The results of this study are expected to contribute to optimizing postoperative analgesia strategies in total knee arthroplasty.
Trial Details
NCT Number NCT07517159
Lead Sponsor Ankara University
Conditions Osteoarthritis, Knee
Enrollment 61 participants
Start Date 2025-05-31
Primary Completion 2025-11-15 (estimated)
Study Completion 2025-11-15 (estimated)
Updated on ClinicalTrials.gov 2026-04-08