Comparison of Acoustic Variability Index (AVI) and Pulse Pressure Variation (PPV) for Predicting Fluid Responsiveness in Mechanically Ventilated Patients

The goal of this clinical trial is to learn if a new medical device called ResQ works to predict fluid needs in adults undergoing surgery under general anesthesia. The main questions it aims to answer are: * Can the Acoustic Variability Index (AVI) measured by ResQ predict if a participant needs more fluids as accurately as the standard arterial blood pressure-based method (PPV)? * Is the ResQ device safe to use during surgery? Researchers will compare the new method (AVI) to the standard method (PPV) to see if ResQ provides reliable information for managing patient fluids. Participants will: * Undergo their planned surgery as scheduled. * Have a soft probe placed in the esophagus to monitor heart and lung sounds. * Receive a set amount of intravenous (IV) fluid as part of their regular surgery care. * Have their heart function checked before and after the fluids are given.

NCT Number	NCT07516470
Lead Sponsor	Signal House Co., Ltd. Collaborators: Ministry of SMEs and Startups, Korea
Conditions	Fluid Responsiveness Predictability, Hemodynamic Monitoring, Anesthesia, General
Enrollment	122 participants
Start Date	2026-04-13
Primary Completion	2026-07-09 (estimated)
Study Completion	2026-07-14 (estimated)
Updated on ClinicalTrials.gov	2026-07-17