Long Duration High Frequency Ultrasound for the Treatment of Osteoarthritis

The purpose of this study is to assess the ability of long-duration high-frequency continuous-wave therapeutic ultrasound to alleviate knee Osteoarthritis pain over an 12-week period. The primary objective of this study is to evaluate the analgesic effect of ultrasound treatment in subjects suffering from knee Osteoarthritis pain. Secondary objectives are to assess the ability of ultrasound treatment to improve joint function.

NCT Number	NCT07515872
Lead Sponsor	ZetrOZ, Inc.
Conditions	Arthritis, Osteo Arthritis of the Knee
Enrollment	240 participants
Start Date	2026-05-01
Primary Completion	2027-05-31 (estimated)
Study Completion	2028-05-31 (estimated)
Updated on ClinicalTrials.gov	2026-04-07