Clinical Trial

Clinical and Radiographic Evaluation of CGF and Alloplastic Grafting in Participants Undergoing the Socket Shield Technique for Immediate Anterior Maxillary Implant Placement. This Study Assesses Bone Healing and Stability When Managing the Crestal Gap in the Esthetic Zone.

Study acronym: CGF
Not Yet Recruiting
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Summary
The goal of this clinical trial is to evaluate the clinical and radiographic effectiveness of the socket shield technique combined with concentrated growth factor (CGF) and alloplastic graft in promoting bone healing and achieving successful immediate implant placement in the esthetic zone. This prospective case series involves both male and female participants aged 18 years or older who require immediate implant placement in the maxillary anterior segments. The main questions it aims to answer are : Does the combined use of CGF and alloplastic grafting materials with the socket shield technique improve crestal bone levels as measured by CBCT? How does this intervention affect secondary outcomes such as primary implant stability measured via the Osstell implant stability quotient? Participants will: Undergo a socket shield procedure (partial extraction therapy) where the labial root fragment is retained to preserve the buccal bone. Provide a blood sample for the preparation of autologous CGF. Receive simultaneous immediate implant placement. Have a "sticky bone" mixture of CGF and alloplastic graft packed into the jumping gap around the implant. Attend follow-up appointments for clinical assessments and CBCT imaging at 2 weeks and 6 months post-operatively.
Trial Details
NCT Number NCT07514871
Lead Sponsor Cairo University
Conditions Alveolar Ridge Resorption, Bone Loss in the Esthetic Zone, Socket Shield Technique, Partial Extraction Therapy, Immediate Dental Implant Placement, Bone Regeneration Using Concentrated Growth Factor, Alloplastic Bone Grafting
Enrollment 7 participants
Start Date 2026-04-25
Primary Completion 2026-10-01 (estimated)
Study Completion 2026-11-01 (estimated)
Updated on ClinicalTrials.gov 2026-04-07