Clinical Trial

Vitamin C for Gingival Depigmentation

Study acronym: VitC-DePg
Recruiting
View on ClinicalTrials.gov →
Record status
This record was last updated April 7, 2026 (before its estimated May 1, 2026 completion). Its status may not reflect the trial's current state.
Summary
The purpose of this study is to evaluate the clinical and histopathological efficacy of topical vitamin C applications using three modalities (topical gel, microneedling , and mesotherapy) in gingival depigmentation. Assessment includes clinical evaluation, CIELAB analysis via DOPI, and histopathological examination (Fontana-Masson staining).
Trial Details
NCT Number NCT07513727
Lead Sponsor Al-Azhar University
Conditions Gingival Hyperpigmentation, Gingival Melanin Pigmentation
Enrollment 30 participants
Start Date 2025-07-29
Primary Completion 2026-05-01 (estimated)
Study Completion 2026-05-01 (estimated)
Updated on ClinicalTrials.gov 2026-04-07