Clinical Trial

ESTIM-UL: FES for Upper Limb Recovery After Stroke

Study acronym: ESTIM-UL
Not Yet Recruiting
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Summary
Stroke is a leading cause of long-term disability, frequently resulting in impaired upper limb motor function and spasticity. Although Botulinum Toxin Type A (BoNT-A) is effective in reducing focal spasticity, functional recovery of the upper limb often remains limited without intensive, task-specific rehabilitation. Functional Electrical Stimulation (FES), when synchronized with voluntary movement during Task-Oriented Training, may enhance motor recovery by facilitating muscle activation and neuroplasticity. This randomized controlled trial aims to evaluate whether FES combined with Task-Oriented Training is superior to conventional Task-Oriented Training alone in improving upper limb function in post-stroke patients treated with BoNT-A.
Trial Details
NCT Number NCT07513714
Lead Sponsor University of Foggia
Conditions Stroke, Post-Stroke Spasticity, Post-Stroke Hemiparesis
Enrollment 40 participants
Start Date 2026-05-01
Primary Completion 2026-10-01 (estimated)
Study Completion 2026-12-01 (estimated)
Updated on ClinicalTrials.gov 2026-04-07