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Enhancing Physical Reserve to Promote Resilience in Physically Frail Older Adults

Study acronym: MRI exercise
StatusRecruiting
PhaseNot applicable
Started
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Record History

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  1. Primary endpoints: details revised at 1 of 4 entries Show 4 more changesShow less
    • Secondary endpoints: details revised at 7 of 10 entries
    • Study description revised
    • Eligibility criteria expanded, about 4 words
    • Collaborators expanded, about 4 words
  2. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
The goal of this clinical trial is to assess the efficacy of combined aerobic and resistance training in enhancing physical reserve in older adults with physical frailty. Investigator contend that enhanced physical reserve will enable preservation of cognitive and physical function. The main questions aims to answer are: (1) Compared with usual care (i.e., CON), will 3-month aerobic and resistance training (ATRT) improve physical reserve in older adults with physical frailty? (2) Compared with CON, will ATRT lead to changes in the neural network organization? (3) Will improved physical reserve lead to better maintenance of cognitive and physical functioning in spite of presence of white matter hyperintensities (WMH)?
Trial Details
NCT Number NCT07513701
Lead Sponsor The Hong Kong Polytechnic University
Collaborators: University of British Columbia
Conditions
(from sponsor)		 Frailty at Older Adults
Enrollment 224 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov