Clinical Trial

The Effects of Quinoa and Buckwheat on Weight Management and Gut Microbiome

Completed
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Summary
This study aims to compare the effects of quinoa, buckwheat, rice, and bulgur consumption on dietary intake, anthropometric measurements, glycemic response, lipid profile, inflammatory markers, blood pressure, and intestinal microbiome in people with overweight and obesity. The primary hypotheses of the studies were given as follows: Hypothesis 1: H1: In people with overweight and obesity, the addition of quinoa and buckwheat to the diet provides weight loss. H0: In people with overweight and obesity, the addition of quinoa and buckwheat to the diet does not provide body weight loss. Hypothesis 2: H2: In people with overweight and obesity, the addition of quinoa and buckwheat to the diet affects glycemic response. H0: In people with overweight and obesity, the addition of quinoa and buckwheat to the diet does not affect glycemic response. Hypothesis 3: H3: In people with overweight and obesity, the addition of quinoa and buckwheat to the diet affects the blood lipid profile. H0: In people with overweight and obesity, the addition of quinoa and buckwheat to the diet does not affect the blood lipid profile. Hypothesis 4: H4: In people with overweight and obesity, the addition of quinoa and buckwheat to the diet changes the composition of the gut microbiome. H0: In people with overweight and obesity, the addition of quinoa and buckwheat to the diet does not change the composition of the gut microbiome. Hypothesis 5: H5: In people with overweight and obesity, the addition of quinoa and buckwheat to the diet increases alpha diversity in the intestinal microbiome. HO: In people with overweight and obesity, the addition of quinoa and buckwheat to the diet does not increase alpha diversity in the intestinal microbiome. Hypothesis 6: H6: In people with overweight and obesity, the addition of quinoa and buckwheat to the diet increases beta diversity in the intestinal microbiome. HO: In people with overweight and obesity, the addition of quinoa and buckwheat to the diet does not increase beta diversity in the intestinal microbiome.
Trial Details
NCT Number NCT07513610
Lead Sponsor Hacettepe University
Conditions Overweight, Obesity
Enrollment 148 participants
Start Date 2024-01-24
Primary Completion 2025-01-17 (estimated)
Study Completion 2025-02-08 (estimated)
Updated on ClinicalTrials.gov 2026-04-07