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Anisodine Hydrobromide for Patients With Acute Ischemic Stroke Undergoing Endovascular Therapy (HEAL)

Study acronym: HEAL
StatusActive, Not Recruiting
PhasePhase 1
Started
View on ClinicalTrials.gov ↗
Trial flagged as At Risk
Primary completion moved at least 3 months later Aug 20, 2026 → Nov 20, 2026
See other at-risk trials from Capital Medical University

Record History

  1. Enrollment closed, study ongoing
    • Primary completion pushed from Aug 20, 2026 to Nov 20, 2026
    • Site details revised at 10 of 10 sites
    v5
  2. Trial sites expanded: 2 → 10 locations
    • Primary completion date: Aug 1, 2026 to Aug 20, 2026
    • Study completion date: Oct 30, 2026 to Nov 20, 2026
    v4
  3. Recruitment opened
    • Study sites: 1 to 2
    • Start date changed from estimate of Apr 15, 2026 to Apr 28, 2026
    v3
  4. Secondary endpoints: details revised at 1 of 6 entriesv2
  5. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
This study is an investigator-initiated Phase 1b clinical trial employing an open-label, non-randomized, dose-escalation design. The primary objective is to evaluate the safety and tolerability of the investigational intervention and to determine the recommended dose for subsequent clinical studies.
Trial Details
NCT Number NCT07513233
Lead Sponsor Capital Medical University
Conditions
(from sponsor)		 Acute Ischemic Stroke
Related terms Ischemic Stroke, Stroke
Enrollment 92 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov