Health-Related Lifestyle Factors, Sex, and Neural Mechanosensitivity in University Students

This observational cross-sectional study aims to investigate the effects of health-related lifestyle factors and sex on neural mechanosensitivity in university students. Specifically, the study will examine whether alcohol consumption, smoking status, physical activity level, age, body mass index, and sex are associated with pressure pain thresholds of the tibial and peroneal nerves. Participants will be university students aged 18 to 30 years enrolled at Fenerbahçe University who voluntarily agree to participate and provide informed consent. Students with neurological disorders, lower extremity musculoskeletal injury or surgery, acute pain, systemic conditions affecting nerve sensitivity, skin problems at the measurement sites, or use of medications that may influence the measurements will be excluded. Data will be collected face to face. Participants will complete a personal information form including demographic characteristics and lifestyle-related factors. Neural mechanosensitivity will be assessed by measuring pressure pain threshold over the tibial and peroneal nerve regions using a digital algometer. Three measurements will be obtained at each site and the average value will be used for analysis. The study is expected to improve understanding of factors associated with peripheral nerve mechanosensitivity in young adults and may provide a scientific basis for future clinical and epidemiological research.

NCT Number	NCT07511452
Lead Sponsor	Fenerbahce University
Conditions	University Students, Health-related Lifestyle Factors, Neural Mechanosensitivity
Enrollment	55 participants
Start Date	2026-03-30
Primary Completion	2026-06 (estimated)
Study Completion	2026-06 (estimated)
Updated on ClinicalTrials.gov	2026-04-06