Clinical Trial

Comparison of WaveOne and ProTaper Systems on Postoperative Pain in Irreversible Pulpitis Patients

Study acronym: WOPP-IP
Completed
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Summary
This study aims to compare two commonly used root canal instrumentation systems, WaveOne (reciprocating system) and ProTaper (rotary system), in patients diagnosed with symptomatic irreversible pulpitis. Root canal treatment is performed to remove inflamed pulp tissue, disinfect the canal, and relieve pain. However, some patients experience pain after the procedure, particularly within the first few days. In this randomized controlled trial, 146 patients will be assigned to receive root canal treatment using either WaveOne or ProTaper instruments. All procedures will be performed under standardized clinical conditions by a single operator. Patients will be asked to record their pain levels using a Numerical Rating Scale (NRS) at specific time intervals after treatment, including 6, 12, 24, 48, and 72 hours, and at one week. The purpose of this study is to determine whether one instrumentation system results in less postoperative pain compared to the other. The findings may help improve patient comfort and guide dentists in selecting the most appropriate root canal instrumentation technique.
Trial Details
NCT Number NCT07510490
Lead Sponsor Armed Forces Institute of Dentistry, Pakistan
Conditions Symptomatic Irreversible Pulpitis
Enrollment 146 participants
Start Date 2025-08-11
Primary Completion 2026-01-18 (estimated)
Study Completion 2026-01-29 (estimated)
Updated on ClinicalTrials.gov 2026-04-03