Clinical Trial

Artificial Intelligence-Based Evaluation of Chest X-Rays in Ventilator-Associated Pneumonia

Completed
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Summary
Ventilator-associated pneumonia (VAP) is a common and serious infection in critically ill patients receiving mechanical ventilation in intensive care units (ICUs). One of the key diagnostic criteria for VAP is the presence of a new or progressive infiltrate on chest X-ray; however, interpretation of bedside chest radiographs is often challenging and subject to inter-observer variability. This retrospective observational study aims to evaluate the role of artificial intelligence (AI) in the assessment of chest X-rays in patients with VAP. Chest radiographs obtained before and at the time of VAP diagnosis will be analyzed using a deep learning-based AI tool (Chester the AI Radiology Assistant), and changes in "infiltration" and "pneumonia" probability scores will be assessed. AI-based findings will be compared with clinical decisions and independent radiologist evaluations regarding the presence of new infiltrates. The study aims to determine the level of agreement between these approaches and to explore whether AI-based analysis can support a more objective and standardized interpretation of chest radiographs in the diagnosis of VAP.
Trial Details
NCT Number NCT07509697
Lead Sponsor Dr Abdurrahman Yurtaslan Ankara Oncology Training and Research Hospital
Conditions Ventilator-Associated Pneumonia, Intensive Care Unit (ICU), Pneumonia, Bacterial, Artificial Intelligence (AI), Radiography, Thoracic
Enrollment 119 participants
Start Date 2026-03-01
Primary Completion 2026-03-20 (estimated)
Study Completion 2026-03-25 (estimated)
Updated on ClinicalTrials.gov 2026-04-03