Clinical Trial

Effect Of Electroacupuncture With Local Anesthesia On Pain And Stress During Impacted Lower Third Molar Surgery

Study acronym: EASE
Not Yet Recruiting
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Summary
This randomized controlled trial investigates the effect of electroacupuncture as an adjunct to local anesthesia on perioperative pain and stress during ambulatory surgical extraction of impacted lower third molars. Participants will be randomized into three groups: electroacupuncture, sham acupuncture, and control. Pain intensity and perceived stress will be assessed using validated scales, while biological stress and nociceptive markers (salivary cortisol, alpha-amylase, and substance P), as well as hemodynamic parameters (blood pressure and heart rate), will be measured. The study aims to provide an integrated evaluation of the effects of electroacupuncture on subjective, biological, and physiological indicators of perioperative response in oral surgery.
Trial Details
NCT Number NCT07509294
Lead Sponsor University of Zagreb
Conditions Postoperative Pain, Stress, Psychological, Impacted Lower Third Molar
Enrollment 60 participants
Start Date 2026-04-20
Primary Completion 2026-10-05 (estimated)
Study Completion 2026-12-18 (estimated)
Updated on ClinicalTrials.gov 2026-04-03