Clinical Trial

Impact of Implementation Strategies on Lp(a) Testing in Secondary Care Settings

Study acronym: Lp(a)CCELERATE
Recruiting
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Summary
Lipoprotein(a) \[Lp(a)\] is recognised as an independent, non-modifiable genetic risk factor for cardiovascular (CV) disease. Current guidelines from the European Society of Cardiology (ESC) and the European Atherosclerosis Society (EAS) recommend that Lp(a) be measured at least once in every adult's lifetime, however routine Lp(a) testing rates remains infrequent. The aim of this study is to assess the impact of implementation strategies (IStr) designed to increase the adoption of Lp(a) testing in routine practice, ultimately leading to more individuals being tested in secondary care. This, in turn, is expected to result in the identification and enhanced management of Cardiovascular Disease (CVD) risk patients with elevated Lp(a).
Trial Details
NCT Number NCT07508007
Lead Sponsor Novartis Pharmaceuticals
Conditions Implementing EAS/ESC Guideline Recommendation on Lp(a) Testing in Routine Practice
Enrollment 4,500 participants
Start Date 2025-11-28
Primary Completion 2028-03-31 (estimated)
Study Completion 2028-03-31 (estimated)
Updated on ClinicalTrials.gov 2026-04-02