This study aimed to evaluate the effect of a cognitive-behavioral approach-based stress management psychoeducation program on the depression, anxiety, and stress levels of nursing students. The study was conducted with undergraduate nursing students studying at the Faculty of Health Sciences of a university. Students in the experimental group received a structured stress management psychoeducation program based on the cognitive-behavioral approach. The control group received no intervention. Data were collected three times using self-report questionnaires: before, after, and three months after the intervention.