Clinical Trial

Impact of Saccharin and Acesulfame-Potassium on Glycemia

Completed
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Summary
The major purpose of this research project is to learn if consuming artificial sweeteners have any impact on glucose levels in adults at high risk for developing type 2 diabetes. People may be at risk for diabetes if you are a middle-aged or older adult. Briefly, the full study is 3 weeks long with 3 controlled feeding visits. Which means participants will eat all of the food and drinks that we provide to them for breakfast. Participants will come to the lab in the morning to eat breakfast, and we will monitor changes in blood glucose over a 2 hour period. Participants will be randomized into 1 of 3 groups: 1 group will receive acesulfame-potassium, 1 group will receive saccharin, and 1 group will receive no artificial sweeteners. Participants will experience a different group each visit, with about 7 days between each visit. We will be examining if consuming artificial sweeteners has any impact on glucose levels.
Trial Details
NCT Number NCT07506577
Lead Sponsor Virginia Polytechnic Institute and State University
Conditions Prediabetes
Enrollment 14 participants
Start Date 2022-07-30
Primary Completion 2025-03-05 (estimated)
Study Completion 2025-05-01 (estimated)
Updated on ClinicalTrials.gov 2026-04-01