Holmium Laser Versus Cold Knife Treatment in Urethral Strictures

The goal of this study is to assess the efficacy of optical internal urethrotomy, which uses a holmium laser in comparison to a cold knife, in treating short-segment urethral strictures in our local setting. The study will help standardize treatment protocols for urethral stricture based on functional results. The local findings will encourage adoption of minimally invasive laser techniques in public hospitals, improving access to modern urologic care. The study will help in informed decision making, enabling patients to understand treatment options and their expected outcomes based on evidence.

NCT Number	NCT07505316
Lead Sponsor	Shahida Islam Medical Complex
Conditions	Stricture Urethra, Holmium Laser, Recurrence
Enrollment	60 participants
Start Date	2026-01-15
Primary Completion	2026-03-14 (estimated)
Study Completion	2026-03-15 (estimated)
Updated on ClinicalTrials.gov	2026-04-21