Clinical Trial

Influence of Training Session Duration on Improvements in Physiological Resilience to Exercise

Study acronym: RED
Recruiting
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Summary
During prolonged endurance exercise, certain physiological variables deteriorate depending on the duration of the exercise. Physiological resilience has therefore been defined as the ability to resist these changes and appears to be an important performance factor in endurance sports. For example, most studies in this field have investigated changes in cycling power output associated with the first ventilatory threshold (VT1), a marker of an individual's endurance capacity, after prolonged endurance exercise. To date, only two studies have examined the effects of training on resilience. The first compared the effectiveness of two training programs, one with low-intensity sessions and the other with high-intensity sessions, with no difference between the conditions. The second study showed that incorporating strength training into a running training program was more effective at improving resilience than running alone. However, the influence of training session duration on resilience remains unknown. Only one observational study has shown that in a group of runners of similar ability, those who were used to doing long sessions had better resilience than those who only did short sessions.
Protocol Amendment History 2 changes
critical Recruitment opened 2026-04-15
notable Primary completion pushed: 2026-04-01 -> 2028-11-15 2026-04-15
Trial Details
NCT Number NCT07504003
Lead Sponsor Centre Hospitalier Universitaire de Saint Etienne
Conditions Endurance Exercise, Healthy Volunteers
Enrollment 40 participants
Start Date 2026-04-08
Primary Completion 2028-11-15 (estimated)
Study Completion 2029-02-28 (estimated)
Updated on ClinicalTrials.gov 2026-04-14