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AMAZE 12: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Maintain Their Weight Loss

Name: AMAZE 12: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight Maintain Their Weight Loss — clinical trial record (NCT07503210)
Creator: DataLookout
License: https://creativecommons.org/licenses/by/4.0/

Study acronym: AMAZE 12

StatusRecruiting

PhasePhase 3

SponsorNovo Nordisk A/S

Started2026-04-21

View on ClinicalTrials.gov ↗

The purpose of this clinical study is to find out if NNC0487-0111 is safe and effective for treating people who have excess body weight. There are 2 study treatments in this study taken as injections under the skin once a week. Participants will either get NNC0487-0111 (the treatment being tested) or Placebo (a treatment that has no active medicine in it). Which treatment participants get is decided by chance.

Amendment history 1 change detected by DataLookout

2026-05-06

Recruitment opened

Trial Details

NCT Number	NCT07503210
Lead Sponsor	Novo Nordisk A/S
Conditions	Obesity
Enrollment	600 participants
Start Date	2026-04-21
Primary Completion	2028-06-06 (estimated)
Study Completion	2028-07-04 (estimated)
Updated on ClinicalTrials.gov	2026-08-27