Clinical Trial

Dose-Response Impact of Geranylgeraniol (GG) Supplementation on Muscle Health

Study acronym: GGE
Recruiting
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Record status
This record was last updated March 31, 2026 (before its estimated August 1, 2026 completion). Its status may not reflect the trial's current state.
Summary
This study will evaluate the effects of daily geranylgeraniol (GG) supplementation on muscular strength, body composition, and aerobic capacity in healthy, physically active men and women. Approximately 60 participants aged 30-60 years will be enrolled in a randomized, double-blind, placebo-controlled, parallel-group trial lasting 8 weeks. Participants will be assigned to receive either placebo, 150 mg GG, or 300 mg GG daily. Outcome measures will be assessed at baseline, week 4, and week 8 and include maximal strength (1RM bench press and leg press), fat-free mass, muscular endurance, aerobic capacity (VO2peak), and circulating biomarkers related to metabolism and health.
Trial Details
NCT Number NCT07502924
Lead Sponsor Lindenwood University
Conditions Muscle Health, Muscle Strength, Body Composition
Enrollment 70 participants
Start Date 2025-03-03
Primary Completion 2026-08-01 (estimated)
Study Completion 2026-08-01 (estimated)
Updated on ClinicalTrials.gov 2026-03-31