Recombinant Tropomyosin- and Hemocyanin-Specific IgE in Children With Suspected Shrimp Allergy

This study will evaluate whether blood tests that measure IgE antibodies to two shrimp proteins, tropomyosin and hemocyanin, can help diagnose shrimp allergy in children. Children with suspected IgE-mediated shrimp allergy will undergo oral food challenge, skin prick testing, and blood sampling. Oral food challenge results will be used as the reference standard to determine whether these tests can accurately identify true shrimp allergy and help improve diagnosis in clinical practice.

NCT Number	NCT07501325
Lead Sponsor	University of Medicine and Pharmacy at Ho Chi Minh City Collaborators: Children's Hospital Number 1, Ho Chi Minh City, Vietnam
Conditions	Food Hypersensitivity, Shellfish Allergy
Enrollment	129 participants
Start Date	2026-04
Primary Completion	2028-03 (estimated)
Study Completion	2028-04 (estimated)
Updated on ClinicalTrials.gov	2026-04-06