Clinical Trial

Performance of an OCR-Prompt-LLM Integrated Workflow for Extracting Multi-dimensional Clinical Data in Ischemic Heart Disease

Study acronym: OPAL-CAD
Completed
View on ClinicalTrials.gov →
Summary
This research aims to evaluate a comprehensive AI-driven workflow for both clinical data extraction and diagnostic classification in coronary artery disease (CAD). Leveraging OCR and Large Language Models (LLMs), the system is designed to extract ten key clinical parameters (such as LVEF and lab results) and provide diagnostic subtypes (UA, STEMI, NSTEMI, CCS) directly from unstructured inpatient records. A man-machine comparative trial will be conducted using a test set of 308 patients, where the performance of the LLM-based workflow will be benchmarked against the average diagnostic accuracy and processing time of seven clinical physicians. The findings will provide evidence for the feasibility of using LLMs to enhance clinical data structuring and diagnostic efficiency in cardiology.
Trial Details
NCT Number NCT07499830
Lead Sponsor China National Center for Cardiovascular Diseases
Conditions Coronary Artery Disease, Artificial Intelligence (AI), Data Collection
Enrollment 308 participants
Start Date 2026-02-23
Primary Completion 2026-03-01 (estimated)
Study Completion 2026-03-02 (estimated)
Updated on ClinicalTrials.gov 2026-03-30