Clinical Trial

Gut Microbiome in DLBCL Treated With Glofitamab

Not Yet Recruiting
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Summary
The gut microbiome (GM) has recently emerged as one of the key modifiable factors of response and prognosis to immunotherapy in cancer patients. Currently, it is unknown if GM also modulates anti-tumor responses to T cell engagers (TCE) including glofitamab in DLBCL patients.
Trial Details
NCT Number NCT07498920
Lead Sponsor Peking Union Medical College Hospital
Conditions DLBCL, Glofitamab, Gut Biome
Enrollment 30 participants
Start Date 2026-04-01
Primary Completion 2029-04-01 (estimated)
Study Completion 2029-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-03-27