Clinical Trial

Effects of Different-Frequency Electroacupuncture on Suprahyoid Muscles in Post-Stroke Dysphagia: Efficacy and Neural Networks

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Summary
This randomized controlled study in patients with post-stroke dysphagia aims to determine the optimal stimulation frequency of electroacupuncture of the suprahyoid muscles and to elucidate the underlying neural mechanisms. Participants will be assigned to low-frequency (2 Hz), medium-frequency (50 Hz), or high-frequency (100 Hz) electroacupuncture groups. Therapeutic efficacy will be assessed using the Kubota water-drinking test, videofluoroscopic swallowing study (VFSS), and ultrasonography to identify the optimal frequency. In parallel, diffusion tensor imaging (DTI) will be used to evaluate changes in fiber connectivity between swallowing-related cortical regions (bilateral precentral gyrus, insula, supramarginal gyrus, and frontal lobe) and the medullary nucleus tractus solitarius, thereby exploring neural network remodeling and providing mechanistic evidence to inform clinical practice.
Trial Details
NCT Number NCT07496762
Lead Sponsor Kaili Chen
Conditions Stroke Sequelae, Deglutition Disorders, Acupuncture Therapy, Electroacupuncture
Enrollment 90 participants
Start Date 2026-04-21
Primary Completion 2028-12-21 (estimated)
Study Completion 2028-12-21 (estimated)
Updated on ClinicalTrials.gov 2026-03-27