Measurement Properties of Mechanical Cost of Walking for Individuals With Walking Impairment

Walking impairment following neurologic injury can increase the energy cost of walking threefold, acting as a functional barrier to independence. The goal of this cross-sectional study is to determine the measurement properties of a novel biomechanical cost of walking measure in chronic stroke capable of pinpointing the origins of movement inefficiencies. This research aims to: 1. determine the convergent validity of biomechanical cost of walking with functional measures in relation to metabolic cost of walking, 2. determine the reliability of biomechanical cost of walking in relation to metabolic cost of walking, 3. determine the responsiveness of biomechanical cost of walking in relation to metabolic cost of walking. Individuals with walking impairment from stroke will complete three 5-minute comfortable speed treadmill walking trials. The 3rd walking trial will be against resistance to increase cost of walking. This single session study will compare the metric properties of biomechanical cost of walking in relation to metabolic cost of walking.

NCT Number	NCT07494890
Lead Sponsor	University of Cincinnati
Conditions	Stroke
Enrollment	18 participants
Start Date	2026-06-25
Primary Completion	2027-03-01 (estimated)
Study Completion	2027-03-01 (estimated)
Updated on ClinicalTrials.gov	2026-07-06