Clinical Trial

Acute Analgesic Effects of MDMA on Experimentally Induced Acute Pain, Hyperalgesia and Allodynia in Healthy Participants

Study acronym: MDPS
Recruiting Phase 1
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Summary
This study investigates whether MDMA may have a pain-reducing effect. The effect of MDMA is compared with a placebo (a substance with no active effect). In the study, moderate pain will be artificially created in healthy participants using repeated small electrical pulses applied under the skin. At the same time, participants will take MDMA or a placebo by mouth. This allows researchers to compare how MDMA affects the artificially created pain. A total of 20 healthy volunteers will take part in this study.
Trial Details
NCT Number NCT07494214
Lead Sponsor University Hospital, Basel, Switzerland
Conditions Healhty
Enrollment 20 participants
Start Date 2026-03-09
Primary Completion 2027-03-09 (estimated)
Study Completion 2027-04-09 (estimated)
Updated on ClinicalTrials.gov 2026-03-27