Clinical Trial

Spontaneous Breathing Mode: A Risk for Hypoxemia During OLV?

Study acronym: OLV
Enrolling by Invitation
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Record status
This record was last updated March 27, 2026 (before its estimated June 30, 2026 completion). Its status may not reflect the trial's current state.
Summary
Patients undergoing thoracic surgery with one-lung ventilation (OLV) are prone to hypoxemia, which is primarily attributable to pulmonary ventilation-perfusion (V/Q) mismatch. This study will preoperatively assess the distribution of pulmonary ventilation under spontaneous breathing and intraoperatively record the lowest peripheral oxygen saturation (SpO₂) during OLV. The aim is to investigate the correlation between these two parameters. The findings are expected to facilitate the prediction of hypoxemia in thoracic surgical patients undergoing OLV.
Trial Details
NCT Number NCT07494006
Lead Sponsor Peking University People's Hospital
Conditions Lung Cancer, OLV, Hypoxemia During Surgery
Enrollment 44 participants
Start Date 2025-07-15
Primary Completion 2026-06-30 (estimated)
Study Completion 2026-12-31 (estimated)
Updated on ClinicalTrials.gov 2026-03-27