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Pilot Exploration of Platelet Characterization of Platelet Rich Plasma Created by Two Different Systems

Study acronym: PRP-PEPC
StatusRecruiting
PhasePhase 4
Started2026-09-01
View on ClinicalTrials.gov ↗

Amendment history

2026-08-17
Study Status, Contacts/Locations v2
Recruitment opened
Start date2026-07-01→2026-09-01
Study sitesdetails revised at 1 of 1 site
2026-06-08
Study Status v1
Primary completion pushed: 2028-03 → 2028-09
Start date2026-03→2026-07-01
2026-03-18
Original filing
The investigators would like to study the differences in the quality of Platelet Rich Plasma (PRP) between two different machines in those with knee osteoarthritis. Knee osteoarthritis means your cartilage has been worn down, and it affects your knee joint. Both machines, the APEX Biologix XCELL PRP System and the Emcyte PurePRP Supraphysiologic Concentrating System, are FDA approved, commercially available, and makes PRP. The investigators will check if the platelets in the PRP have different amounts or work differently. The investigators will also assess participants symptoms after the injection and compare the two different preparation systems.
Trial Details
NCT Number NCT07491367
Lead Sponsor University of California, San Francisco
Conditions Knee Osteoarthristis, Cartilage Damage, Platelet Rich Plasma, Platelet Rich Plasma Injection
Enrollment 20 participants
Start Date 2026-09-01
Primary Completion 2028-09 (estimated)
Study Completion 2028-09 (estimated)
Updated on ClinicalTrials.gov 2026-08-18