Clinical Trial

Effect Of Trendelenburg Position And Pneumoperitoneum On Optic Nerve Sheath Diameter In Robot-Assisted Prostatectomy

Study acronym: ONSD-RALP
Recruiting
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Record status
This record was last updated March 24, 2026 (before its estimated June 2026 completion). Its status may not reflect the trial's current state.
Summary
This prospective study aims to evaluate the effect of steep Trendelenburg position and pneumoperitoneum on optic nerve sheath diameter in patients undergoing robot-assisted laparoscopic radical prostatectomy and open radical prostatectomy under general anesthesia. Increased intracranial pressure may occur during robotic surgery due to pneumoperitoneum and head-down positioning. Optic nerve sheath diameter measured by ocular ultrasonography is a non-invasive method used to assess intracranial pressure changes. Hemodynamic and respiratory parameters will also be recorded during surgery. The results of this study may help to better understand the physiological effects of surgical position and pneumoperitoneum during prostatectomy procedures.
Trial Details
NCT Number NCT07491198
Lead Sponsor Ege University
Conditions Prostate Cancer, Optic Nerve Sheath Diameter, Robot-Assisted Radical Prostatectomy, Steep Trendelenburg Position With Penumoperitoneum in Robot Assisted Laparoscopic Prostatectomy
Enrollment 50 participants
Start Date 2026-01-05
Primary Completion 2026-06 (estimated)
Study Completion 2026-09 (estimated)
Updated on ClinicalTrials.gov 2026-03-24