Clinical Trial

Retrospective Comparison of Tubular Decompression ± Rhizotomy Versus TLIF in Lumbar Spinal Stenosis

Study acronym: TUBE-FUSE
Completed
View on ClinicalTrials.gov →
Summary
This retrospective observational study examines clinical outcomes in patients with lumbar spinal stenosis who underwent minimally invasive tubular decompression, with or without subsequent multisegmental percutaneous rhizotomy, at the General University Hospital of Valencia over 25 years (2000-2025). The purpose of the study is to determine whether decompression alone provides sufficient long-term symptom improvement or whether additional spinal fusion (transfacetal TLIF) is needed in specific patient subgroups. By analyzing real-world data from routine clinical practice, this study aims to identify clinical, radiological, and demographic factors associated with the need for fusion surgery, particularly in older adults who may benefit from less invasive treatment strategies. No new interventions are performed as part of this study, and all data are obtained from existing medical records.
Trial Details
NCT Number NCT07489508
Lead Sponsor University of Valencia
Collaborators: Hospital General Universitario de Valencia
Conditions Lumbar Spinal Stenosis, Degenerative Lumbar Spondylolisthesis, Neurogenic Claudication
Enrollment 246 participants
Start Date 2000-01-01
Primary Completion 2026-03-01 (estimated)
Study Completion 2026-03-04 (estimated)
Updated on ClinicalTrials.gov 2026-03-24