Clinical Trial

Impact of Protein Source and Polyphenol Complexation in Protein Bars on Metabolic Health

Study acronym: POLYPRO
Active, Not Recruiting
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Summary
The goal of this clinical trial is to learn if pulse (pea) protein works similar to animal (whey) protein in protein bars consumed by healthy adults. The main questions it aims to answer are: What are the differences in taste and tolerance profiles between pea and whey proteins? What metabolic and immune changes do participants experience while eating them? What gastrointestinal microbiome shifts can be observed in these participants? How incorporation and complexation of polyphenols with these proteins changes the study outcomes? Participants will: Consume 1 protein bar with whey protein, pea protein, pea protein with complexed polyphenols, or pea protein with free polyphenols every day for 2 months. Visit the study site at baseline and end of study for checkups and tests. Fill dietary, food acceptance, gastrointestinal tolerance, and global health questionnaires.
Trial Details
NCT Number NCT07489118
Lead Sponsor North Carolina State University
Conditions Food Acceptance, Metabolic Health, Immune Cells Activity, Microbiome Composition
Enrollment 72 participants
Start Date 2025-05-01
Primary Completion 2025-09-08 (estimated)
Study Completion 2026-04-01 (estimated)
Updated on ClinicalTrials.gov 2026-03-23