Evaluation of Mandibular Bone Microstructure Changes After Periodontal Treatment (M-BONE Study)

This prospective study evaluates how non-surgical treatment for gum disease affects the bone of the mandible. Gum disease (periodontitis) can lead to changes in the bone supporting the teeth, but these changes are not always easy to detect with routine clinical examination. prospectively collect clinical and radiographic data from patients with moderate and severe gum disease (Stage II and Stage III periodontitis), as well as individuals with gingivitis, were analyzed. All participants had received standard periodontal treatment as part of routine care. Radiographic images taken before treatment and 6 months after treatment were examined using fractal analysis, a method used to assess bone structure. The results of this study may help improve understanding of how periodontal treatment influences bone structure and may support the use of radiographic analysis as a tool for monitoring treatment outcomes.

NCT Number	NCT07488403
Lead Sponsor	Akdeniz University
Conditions	Periodontitis, Gingivitis
Enrollment	69 participants
Start Date	2023-01-01
Primary Completion	2024-01-01 (estimated)
Study Completion	2024-01-01 (estimated)
Updated on ClinicalTrials.gov	2026-07-22