Clinical Trial

Migraine Prevention With the Remote Electrical Neuromodulation (REN) Wearable: A Real-world Evidence Study

Completed
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Summary
Preventive pharmacologic therapies for migraine aim to reduce attack frequency and duration and improve quality of life; however, their use, overall benefit and adherence are often limited. Remote electrical neuromodulation (REN) is a non-invasive FDA-cleared wearable device for acute and/or preventive migraine treatment. This study will evaluate the real-world efficacy and patient-reported outcomes of preventive REN use over 3 months in migraine patients.
Protocol Amendment History 2 changes
critical Trial completed 2026-07-02
notable Enrollment increased: 150 -> 332 participants 2026-07-02
Trial Details
NCT Number NCT07487701
Lead Sponsor Theranica
Conditions Migraine
Enrollment 332 participants
Start Date 2026-02-20
Primary Completion 2026-04-15 (estimated)
Study Completion 2026-04-15 (estimated)
Updated on ClinicalTrials.gov 2026-07-01