Clinical Trial

G8 Screening Tool Validation in Older Adults With Cancer in Portugal

Study acronym: G8-PT
Not Yet Recruiting
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Summary
The G8 screening tool is widely recommended for the identification of frailty in older adults with cancer. However, prospective validation data in the Portuguese population are currently lacking. This prospective observational study aims to evaluate the diagnostic performance of the G8 screening tool compared with a Comprehensive Geriatric Assessment (CGA) in older adults with cancer. Patients aged ≥70 years with solid tumors will be assessed using both the G8 screening tool and a multidimensional CGA. Frailty will be defined as impairment in at least one CGA domain. The performance of the G8 will be evaluated in terms of sensitivity, specificity, and area under the receiver operating characteristic curve. This study aims to provide the first prospective validation of the G8 screening tool in Portuguese older adults with cancer and to support its implementation in clinical practice.
Trial Details
NCT Number NCT07487298
Lead Sponsor Hospital de Braga
Conditions Cancer, Frailty, Aged
Enrollment 150 participants
Start Date 2026-03-20
Primary Completion 2027-06-30 (estimated)
Study Completion 2027-12-15 (estimated)
Updated on ClinicalTrials.gov 2026-03-23