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The Efficacy and Safety of a Single-Dose Hyaluronic Acid Injection in the Treatment of Knee Osteoarthritis

Study acronym: ESSDHAITKO
StatusNot Yet Recruiting
PhaseNot specified
Started
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Record status
This record was last updated April 29, 2026 (before its estimated May 15, 2026 completion). Its status may not reflect the trial's current state.

Record History

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  1. Start date: Mar 20, 2026 to May 1, 2026
    • Primary and study completion dates: Apr 20, 2026 to May 15, 2026
    • Collaborators shortened, about 2 words
    v2
  2. Study First Submitted
  • Stopped: an ongoing trial was terminated, suspended or withdrawn.
  • Notable: the trial’s plan changed such as a big move in its timeline or size, a new primary endpoint, sponsor or phase, or recruiting opened or resumed.
  • Minor: routine progress and housekeeping, such as sites added or enrollment closed.
HA therapy typically consists of several intra-articular injections administered at weekly intervals. A single-dose IA-HA treatment offers patients and physicians a treatment option that involves both lower costs and fewer clinic visits. Furthermore, considering the administration procedure, we believe that single-dose therapy helps reduce the risk of potential side effects. In light of this information, our study aims to retrospectively evaluate the efficacy and safety of HA in patients with symptomatic knee OA who have received a single-dose intra-articular HA injection.
Trial Details
NCT Number NCT07487038
Lead Sponsor Fatih Sultan Mehmet Training and Research Hospital
Conditions
(from sponsor)		 Knee Osteoarthristis, Hyaluronic Acid
Enrollment 133 participants
Start Date
Primary Completion (estimated)
Study Completion (estimated)
Updated on ClinicalTrials.gov