Clinical Trial

The Efficacy and Safety of a Single-Dose Hyaluronic Acid Injection in the Treatment of Knee Osteoarthritis

Study acronym: ESSDHAITKO
Not Yet Recruiting
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Record status
This record was last updated April 29, 2026 (before its estimated May 15, 2026 completion). Its status may not reflect the trial's current state.
Summary
HA therapy typically consists of several intra-articular injections administered at weekly intervals. A single-dose IA-HA treatment offers patients and physicians a treatment option that involves both lower costs and fewer clinic visits. Furthermore, considering the administration procedure, we believe that single-dose therapy helps reduce the risk of potential side effects. In light of this information, our study aims to retrospectively evaluate the efficacy and safety of HA in patients with symptomatic knee OA who have received a single-dose intra-articular HA injection.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2026-03-17.
Trial Details
NCT Number NCT07487038
Lead Sponsor Fatih Sultan Mehmet Training and Research Hospital
Conditions Knee Osteoarthristis, Hyaluronic Acid
Enrollment 133 participants
Start Date 2026-05-01
Primary Completion 2026-05-15 (estimated)
Study Completion 2026-05-15 (estimated)
Updated on ClinicalTrials.gov 2026-04-29