Clinical Trial

Evaluation of Emergency Medicine Pharmacist Impact on Blood Culture Review Following Emergency Department Discharge

Completed
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Summary
Patients are commonly discharged from the Emergency Department(ED) with pending blood culture results. Blood cultures can take up to 48 hours to become positive which is why it is important to notify patients with true positive cultures as soon as possible. Delay in notification can lead to other serious complications such as sepsis, septic shock, and death. The American College of Emergency Physicians states pharmacists serve a critical role in ensuring efficient, safe, and effective medication use in the ED and advocates for health systems to support dedicated roles for pharmacists within the ED. Pharmacists help to decrease the workload on the healthcare team, especially in the ED where there is high volume and acuity.Emergency medicine pharmacist (EMP) play a significant role in the optimization of therapy, medication safety, and reducing costs. There is strong evidence for the positive impact EMPs have on microbiological culture review. Overall, pharmacist review of late cultures results in higher rates of appropriate antimicrobial therapy and decreased missed interventions.These prior studies focused on the review of microbiological tests, including sexually transmitted infections, urine, and wound cultures; however, there was limited data to support the role of pharmacists evaluating late blood culture results.
Protocol Amendment History 4 changes
critical Trial completed 2026-08-05
notable Enrollment increased: 126 -> 146 participants 2026-08-05
notable Primary completion moved earlier: 2027-01-31 -> 2025-01-20 2026-08-05
minor Completion moved earlier: 2028-01-31 -> 2025-01-25 2026-08-05
Trial Details
NCT Number NCT07486362
Lead Sponsor Methodist Health System
Conditions Bacteremia
Enrollment 146 participants
Start Date 2024-01-31
Primary Completion 2025-01-20 (estimated)
Study Completion 2025-01-25 (estimated)
Updated on ClinicalTrials.gov 2026-08-04