Clinical Trial

Artificial Intelligence in Aortic Regurgitation

Recruiting
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Summary
This research project aims to develop and validate a tool that uses artificial intelligence (AI) to automatically detect and quantify aortic regurgitation (AR). The clinical efficacy of this tool will be established by comparing it to manual diagnostic methods in a multicenter randomized controlled trial. By leveraging deep learning (DL) techniques, the AI system will automate aortic regurgitation (AR) detection, measurement, and diagnosis, addressing challenges like variability in echocardiographic interpretations and the need for specialized expertise. It will integrate multiple echocardiographic parameters to provide accurate, standardized, and efficient AR diagnoses, reducing human error and improving consistency. This tool will enhance diagnostic precision and accessibility, improving clinical outcomes and extending advanced diagnostic capabilities to a broader range of healthcare environments, including resource-limited settings.
Trial Details
NCT Number NCT07486271
Lead Sponsor Chinese University of Hong Kong
Collaborators: Semmelweis University, The Prince Charles Hospital, Toho University, Us2.ai, The University of New South Wales
Conditions Aortic Regurgitation Disease
Enrollment 540 participants
Start Date 2025-12-01
Primary Completion 2028-03-31 (estimated)
Study Completion 2028-03-31 (estimated)
Updated on ClinicalTrials.gov 2026-03-20