Clinical Trial

Comparison of Post-Operative Endodontic Pain Using Sodium Hypochlorite, Hydrogen Peroxide, and Normal Saline as Root Canal Irrigants

Study acronym: EPI-RCT
Completed
View on ClinicalTrials.gov →
Summary
Pain is the main reason patients visit a dentist for root canal treatment. Sometimes, patients experience pain between visits, which can make the treatment uncomfortable and stressful. This study aims to compare three commonly used root canal irrigants-sodium hypochlorite, hydrogen peroxide, and normal saline-to see which one causes less pain after treatment. Patients with acute pulpitis who require root canal treatment will be randomly assigned to one of the three irrigant groups. Pain will be measured using a simple Visual Analog Scale (VAS) at specific time points after treatment. The results of this study will help dentists choose the most effective and comfortable irrigant, improving patient experience and reducing the likelihood of unscheduled visits due to pain.
Trial Details
NCT Number NCT07486245
Lead Sponsor CMH Multan Institute of Medical Sciences
Conditions Acute Pulpitis, Post Endodontic Pain
Enrollment 90 participants
Start Date 2025-03-15
Primary Completion 2025-11-13 (estimated)
Study Completion 2025-11-24 (estimated)
Updated on ClinicalTrials.gov 2026-03-20