Magnetic Resonance Imaging of the Lung: Oncological Applications

Lung neoplasms are characterized by a complex interaction between tumor cells and a variety of resident and infiltrating host elements, secreted factors, and extracellular matrix proteins, collectively referred to as the microenvironment. Nowadays, in the setting of lung cancer, and in particular non-small cell lung cancer (NSCLC), the evaluation of microenvironment characteristics can only be performed by a pathologist and only on histological material. By combining different MRI parameters, it may be possible to create a specific imaging "signature" for the three different immune phenotypes and thus be able to make a distinction based on MRI examination.

NCT Number	NCT07486219
Lead Sponsor	Fondazione IRCCS Policlinico San Matteo di Pavia
Conditions	Lung Cancer (NSCLC)
Enrollment	50 participants
Start Date	2020-01-15
Primary Completion	2026-04 (estimated)
Study Completion	2026-04 (estimated)
Updated on ClinicalTrials.gov	2026-03-20