LFP-based Parameter Prediction in DBS for Parkinson's Disease

The goal of this observational study is to assess whether deep brain stimulation (DBS) contact selection in Parkinson's disease could be informed by subcortical local field potential (LFP) recordings. The main question it aims to answer is: Aligns stimulation contact selection based on subcortical LFP recordings with clinically optimized contact selection? Participants will undergo LFP recordings that are part of standard clinical care during their routine hospital visits.

NCT Number	NCT07485621
Lead Sponsor	Loes Laurijssen
Conditions	Parkinson's Disease (PD)
Enrollment	40 participants
Start Date	2026-03-05
Primary Completion	2029-03 (estimated)
Study Completion	2029-03 (estimated)
Updated on ClinicalTrials.gov	2026-03-20