Clinical Trial

Association Between Intraoperative Mean Arterial Pressure Variability and Postoperative Fatigue in Patients Undergoing Laparoscopic Abdominal Surgery

Completed
View on ClinicalTrials.gov →
Summary
This prospective cohort study aims to investigate the relationship between intraoperative mean arterial pressure (MAP) variability and postoperative fatigue syndrome (POFS) in elderly patients (≥18 years) undergoing laparoscopic abdominal surgery. The main research question is: Does the degree of intraoperative MAP fluctuation correlate with postoperative fatigue in elderly patients? Eligible patients scheduled for elective laparoscopic abdominal surgery under general anesthesia will have their intraoperative blood pressure variability recorded (generalized average real variability, G-ARV), and postoperative fatigue and recovery will be assessed on postoperative days 1, 3, and 7 using the Christensen fatigue scale.
Protocol Amendment History 4 changes
critical Trial completed 2026-07-08
notable Primary completion moved earlier: 2026-10-31 -> 2026-06-30 2026-07-08
minor Completion moved earlier: 2026-12-31 -> 2026-06-30 2026-07-08
critical Trial status changed: Not Yet Recruiting → Active, Not Recruiting 2026-07-07
Trial Details
NCT Number NCT07481006
Lead Sponsor The First People's Hospital of Lianyungang
Conditions Fatigue Symptom, Blood Pressure Variability
Enrollment 366 participants
Start Date 2026-04-15
Primary Completion 2026-06-30 (estimated)
Study Completion 2026-06-30 (estimated)
Updated on ClinicalTrials.gov 2026-07-07