This cross-sectional observational study aims to evaluate caregiver burden, fatigue, sleep quality, and depression among family caregivers of stroke patients with lower urinary tract symptoms (LUTS). Stroke survivors frequently experience urinary dysfunction, which may increase caregiving demands and negatively affect caregiver well-being. A total of 70 family caregivers of stroke patients with LUTS receiving inpatient or outpatient rehabilitation care were included. Caregiver outcomes were assessed using validated instruments including the Caregiver Strain Index (CSI), Fatigue Severity Scale (FSS), Pittsburgh Sleep Quality Index (PSQI), and Beck Depression Inventory (BDI). The study also examined the relationship between caregiver outcomes and patient-related clinical variables such as stroke severity and cognitive status.