Clinical Trial

Pain Experience Using Lidocaine Adrenaline Tetracaine (LAT) Gel Versus Lidocaine Infiltration for Laceration Repair in Adults

Completed Phase 4
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Summary
This prospective comparative study evaluates pain experience in adult patients undergoing laceration repair in the emergency department using either topical lidocaine-adrenaline-tetracaine (LAT) gel or lidocaine infiltration as local anaesthesia. Lidocaine infiltration is the standard anaesthetic technique for wound repair but can cause significant pain during injection. LAT gel is a needle-free topical anaesthetic that is widely used in paediatric patients but has been less studied in adults. Adult patients presenting with simple lacerations requiring suturing are allocated to receive either LAT gel or lidocaine infiltration according to the clinical judgement of the treating physician. Pain is measured using a visual analogue scale (VAS) during anaesthetic administration, during testing of anaesthetic effectiveness, and during suturing. Additional variables include wound characteristics, patient characteristics, and the need for additional anaesthesia. The study aims to evaluate whether LAT gel provides comparable pain control while reducing pain during anaesthetic administration.
Trial Details
NCT Number NCT07480135
Lead Sponsor Vrije Universiteit Brussel
Collaborators: Universitair Ziekenhuis Brussel
Conditions Lacerations, Wound Repair, Acute Traumatic Wounds, Pain Management
Enrollment 70 participants
Start Date 2021-04-01
Primary Completion 2021-05-22 (estimated)
Study Completion 2021-05-31 (estimated)
Updated on ClinicalTrials.gov 2026-03-18