A Study on Intratumoral Fibrosis and α-SMA Expression in Intrahepatic Cholangiocarcinoma

The aim of this observational study was to understand the prognostic imaging of the degree of intratumoral fibrosis and intratumoral α-SMA levels in patients with intrahepatic cholangiocarcinoma (ICC). The main questions it aims to answer are: Whether the degree of intratumoral fibrosis and the level of intratumoral α-SMA affect the overall survival and progression-free survival of ICC patients. Participants will be surveyed for survival and tumor recurrence up to 5 years after surgery.

NCT Number	NCT07479264
Lead Sponsor	First Affiliated Hospital, Sun Yat-Sen University
Conditions	Intrahepatic Cholangiocarcinoma (Icc)
Enrollment	169 participants
Start Date	2018-01-01
Primary Completion	2025-01-17 (estimated)
Study Completion	2025-05-01 (estimated)
Updated on ClinicalTrials.gov	2026-03-18