Clinical Trial

Radiation, Oral Vancomycin, and CAR-T for B-Cell Lymphomas

Recruiting Phase 1
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Summary
This clinical trial assesses whether it is feasible to use radiation therapy with vancomycin prior to CAR T-cell therapy for patients with large B-cell lymphomas
Protocol Amendment History 1 change
critical Recruitment opened 2026-07-02
Trial Details
NCT Number NCT07478848
Lead Sponsor Abramson Cancer Center at Penn Medicine
Collaborators: National Cancer Institute (NCI)
Conditions Large B Cell Lymphoma, Non Hodgkin Lymphoma (NHL), Diffuse Large B Cell Lymphoma (DLBCL), Diffuse Large B Cell Lymphoma Refractory, Diffuse Large B Cell Lymphoma Relapsed
Enrollment 14 participants
Start Date 2026-05-29
Primary Completion 2029-01-01 (estimated)
Study Completion 2029-01-01 (estimated)
Updated on ClinicalTrials.gov 2026-07-01