Assessing the Effectiveness of Low-Dose Computed Tomography in Lung Cancer Screening for High-Risk Smokers: A Randomized Controlled Trial in Hong Kong

The investigators propose a randomized controlled trial to evaluate the clinical effectiveness of low-dose computed tomography (LDCT) for lung cancer screening in high-risk Chinese ever-smokers aged 50-79 years in Hong Kong and to assess the cost-effectiveness of implementing LDCT for lung cancer screening in the local setting.

NCT Number	NCT07478757
Lead Sponsor	The University of Hong Kong Collaborators: The Hong Kong Jockey Club Charities Trust
Conditions	Lung Cancer, Lung Cancer Screening
Enrollment	15,000 participants
Start Date	2026-07-01
Primary Completion	2032-06-30 (estimated)
Study Completion	2037-06-30 (estimated)
Updated on ClinicalTrials.gov	2026-03-17