Clinical Trial

Oral Health, Dento-facial Condition and OHRQoL in Subjects With Mowat-Wilson Syndrome: an Epidemiologic Study.

Study acronym: ORALMOWAT26
Not Yet Recruiting
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Record status
This record was last updated March 24, 2026 (before its estimated May 31, 2026 completion). Its status may not reflect the trial's current state.
Summary
Mowat-Wilson Syndrome (MWS) is a rare syndrome characterized by the presence of facial gestalt and delayed psychomotor development, variably associated with intellectual disability, epilepsy, Hirschsprung's disease (HSCR) and multiple congenital malformations. Although there is evidence of the presence of dental and craniofacial anomalies in MWS, little epidemiological data is available to date. The goal of this observational study is to assess oral health and dento-facial phenotype of people affected by Mowat-Wilson Syndrome (MWS). In addition, the Oral Health Related Quality of Life (OHRQoL) will be investigated.
Protocol Amendment History 1 amendment
This ClinicalTrials.gov record has been amended once since 2026-03-11.
Trial Details
NCT Number NCT07476417
Lead Sponsor University of Milan
Collaborators: Associazione Italiana Mowat Wilson (Mowat Wilson Italian Association)
Conditions Mowat-Wilson Syndrome, Dental Caries, Periodontal Diseases, Sleep Related Breathing Disorder, Tooth Diseases, Malocclusion, Tooth Abnormalities, Oral Health Related Quality of Life (OHRQoL) +2 more
Enrollment 25 participants
Start Date 2026-04-01
Primary Completion 2026-05-31 (estimated)
Study Completion 2026-08-30 (estimated)
Updated on ClinicalTrials.gov 2026-03-24