Clinical Trial

Efficacy and Safety of CD7 CAR-T in Newly Diagnosed High-Risk T-LBL/ALL

Not Yet Recruiting Early Phase 1
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Summary
This study is an open, single-center, prospective clinical trial, with newly diagnosed high-risk T-LBL/ALL patients as the subjects. It plans to enroll 10 subjects. All patients will undergo lymphocyte collection during the CR1 remission period, followed by the preparation and reinfusion of CD7 CAR-T cells. Adverse reactions will be followed up and observed, and relevant data on treatment efficacy will be collected to evaluate the safety, efficacy, and cell metabolic kinetics characteristics of CAR-T cell therapy for the patients.
Trial Details
NCT Number NCT07476027
Lead Sponsor Institute of Hematology & Blood Diseases Hospital, China
Conditions T Lymphoblastic Lymphoma, T Acute Lymphoblastic Leukemia
Enrollment 10 participants
Start Date 2026-03-15
Primary Completion 2029-04-01 (estimated)
Study Completion 2029-06-27 (estimated)
Updated on ClinicalTrials.gov 2026-03-17