Clinical Trial

Comparison of Two Biometers in Dense Cataracts

Completed
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Summary
This single-center, ambispective, observational study evaluates axial length acquisition in eyes with dense cataracts using the ARGOS swept-source optical coherence tomography biometer compared with the IOLMaster 700. Eligible subjects are pseudophakic adults who previously underwent complex cataract surgery because of poor visualization or poor red reflex from dense lens opacity and who had pre-operative biometry performed with both devices, with or without manual immersion A-scan ultrasonography. Enrolled subjects return for postoperative repeat biometry to confirm pre-operative measurements and to assess whether availability of an ARGOS axial length measurement may reduce the need for manual ultrasound A-scans in similar dense cataract cases. The planned sample size justification estimated that 61 patients were needed for statistical power, while 68 were originally targeted to allow for attrition in the prospective portion.
Trial Details
NCT Number NCT07475832
Lead Sponsor Berkeley Eye Center
Collaborators: Alcon Research
Conditions Cataract
Enrollment 61 participants
Start Date 2023-10-11
Primary Completion 2025-10-15 (estimated)
Study Completion 2025-10-15 (estimated)
Updated on ClinicalTrials.gov 2026-03-17